Neuromentis®

Neuromentis® - a supplement improving brain function

Neuromentis® is our proprietary supplement, particularly targeted at individuals exposed to factors that negatively affect the nervous system. It is a completely innovative dietary supplement supporting brain function and neurotransmission processes, notable for its unique composition.

The dietary supplement Neuromentis® works best when used in conjunction with our second product, Revimyelin®. Both products have been designed to complement each other and work synergistically, amplifying their impact on the entire body.

Neuromentis® brain function enhancement supplement - for whom?

Depression, brain fog, and chronic fatigue don't come from nowhere and accompany many diseases, including multiple sclerosis (MS). The etiology of all diseases is not entirely known, but we have sufficiently understood the processes occurring in the brain and their effects. As probably everyone knows, a huge number of processes take place in the brain, which are responsible not only for our mental state but also for our physical condition. Biological disturbances in neurotransmitter production can thus lead to dire consequences involving changes in the brain. Apart from depressive mental states, the causes of these changes can also include fatigue, lack of energy, or reduced activity, both in terms of daily functions and at the level of cognitive activity. Especially negative effects can be seen in disorders of neurotransmitter production in people suffering from, among others, MS. Therefore, the Neuromentis® supplement can be a valuable support in the treatment of multiple sclerosis.

Who else is Neuromentis® recommended for? Our product can also serve as a supplement for depression and comprehensively as a supplement for the nervous system.

Neuromentis® brain function support supplement - key benefits:

• The Neuromentis® supplement is based on unique ingredients with proven effects, featuring the maximum concentration of the active substance in each capsule.
• Neuromentis® was developed based on numerous analyses and studies.
• It excels as a supplement for multiple sclerosis (MS), neuroborreliosis, and as a supplement for depression.
• Contains natural ingredients that provide strong and effective support for brain function and the nervous system.
• To ensure the highest quality procedures and control standards, Neuromentis® is manufactured in the EU, meeting ISO 9001:2009, ISO 22000:2006, GMP, and HACCP standards.
• Neuromentis® does not contain any preservatives.

Nervous System Supplements Neuromentis® - more about NADH and NAD+

The largest grouping of dopaminergic neurons is located in the substantia nigra in the midbrain, which is part of the extrapyramidal nervous system. It is responsible for initiating voluntary movements and regulating the tone of skeletal muscles.

Patients with disorders in this component of the nervous system report pathological changes in muscle tone (stiffness in parkinsonism, decreased tone in chorea), the occurrence of involuntary movements (resting tremor in parkinsonism, choreic, athetotic, ballistic, dystonic movements), and difficulties in movement coordination.

As explained by Dr. George Birkmayer, director of the Parkinson's Therapy Institute in Vienna, who has been conducting research on NADH for over 30 years: "one-third of all the energy we produce in our body is used by our brain. For this reason, an energy deficiency appears first in the brain with symptoms such as lack of concentration and alertness or mental fog. With a greater amount of NADH, brain cells function better (...). Another mechanism through which NADH affects cognitive functions is by stimulating the production of adrenaline and dopamine. Both of these substances are essential for our cognitive functioning and our memory" (Interview: Dr. George Birkmayer on NADH for Energy, Healthy Immune Function and More, "ProHealth", January 30, 2006).

In 2004, a randomized double-blind placebo-controlled clinical trial was conducted to investigate the efficacy of NADH in alleviating symptoms of Alzheimer's disease. 24 patients with probable Alzheimer's disease received 10 mg of oral NADH or a placebo. As observed after six months, participants taking NADH did not show signs of progressive cognitive function deterioration; on the contrary, they exhibited significantly higher performance scores than the placebo group in terms of verbal fluency and visuoconstructive abilities, as well as a tendency towards better performance in abstract verbal reasoning. The researchers concluded: "Consistent with previous studies, the current findings support NADH as alleviating symptoms of Alzheimer's disease" (Demarin V., Podobnik S.S., Storga-Tomic D., Kay G., Treatment of Alzheimer's disease with stabilized oral nicotinamide adenine dinucleotide: A randomized, double-blind study, "Drugs Exp Clin Res." 2004;30(1):27–33).

NAD+ activates sirtuins, which are responsible for the longevity and efficient functioning of organs in the body, thereby influencing good physical condition. Clearing metabolic pathways through the increase of NAD+ along with sirtuin activation raises perceivable energy, which is directed both to the nervous system and to the working muscles.

Increased expression of NAD+ leads to a reduction in beta-amyloid toxicity, which is associated with the pathogenesis of Alzheimer's disease. NAD+ is also responsible for regulating inflammatory states in the nervous system by influencing the release of inflammatory cytokines by microglia. As a result, NAD+ reduces the risk of degenerative diseases.

NAD+ influences the production of TH1 and TH17 cytokines of the immune system. These cytokines are involved in the pathogenesis of many autoimmune diseases. NAD+ not only inhibits but also reverses neuron degeneration through immunosuppression induced by an increase in IL10 and accelerated myelination. It has been proven that glial cells supply NAD to neurons in stressful situations. In multiple sclerosis, it has been observed that the level of NAD+ in microglia is disturbed, resulting in increased production of pro-inflammatory cytokines that cause neurodegeneration.

In the case of patients with MS, the level of NAD increases in the immune system and decreases in the nervous system, causing a deficiency in neurons, which in turn are more susceptible to damage during the disease.